A POTENT POSTENTRY RESTRICTION TO PRIMATE LENTIVIRUSES IN A YINPTEROCHIROPTERAN BAT

ABSTRACT Bats are primary reservoirs for multiple lethal human viruses, such as Ebola, Nipah, Hendra, rabies, severe acute respiratory syndrome coronavirus (SARS-CoV), Middle East respiratory syndrome-related coronavirus (MERS-CoV), and, most recently, SARS-CoV-2.The innate immune systems of these immensely abundant, anciently diverged mammals rema

Thymoquinone, an active compound isolated from black cumin seeds (Nigella sativa L.), has pharmacological activity as anticancer, antiinflammatory, and immunomodulator.This compound has a volatile nature, easily oxidized, and low melting point, leading to difficulties in tablet formulation.Moreover, its low solubility in water leading to low bioava